The transition in action: When innovation meets collaboration, even the sky isn't the limit

pMDI Industry trends Sustainability

resource : Video

With the accelerated transition from existing propellants HFA-134a and HFA-227ea, switching to alternative low Global Warming Potential (GWP) propellants in pressurised Metered Dose Inhalers (pMDIs) is an urgent industry priority. Companies must be ready to adapt their manufacturing, clinical testing and regulatory submission processes, and getting ahead of the curve now will pay dividends later. Appropriate planning and expert guidance are vital for ensuring continuity of supply for patients while charting a course for success.

Following the publication of “Championing a Safe Transition to Low Carbon Inhalers” in Pharmaceutical Manufacturing and Packing Sourcer (PMPS), we are excited to dig deeper into the logistics of transitioning to the next generation of propellants. We convened an expert panel to explore the key success factors, and the result was this fascinating roundtable discussion.

Expert Panel

Nick Atkinson

Nick Atkinson is Portfolio Manager for Strategic Engineering Projects at Bespak. Nick has extensive knowledge in the design and implementation of manufacturing systems for orally inhaled and nasal drug products, across all manufacturing scales. Nick has led the implementation of new and adaptions to existing manufacturing processes at clinical and commercial scale, and prior to his current role led the engineering project delivery team.

Markus Laubscher

Markus Laubscher Head of Orbia Fluor & Energy Materials Pharma Business Unit, oversees the company’s position as the global leader in manufacturing and supplying high-purity and low Global Warming Potential (GWP) medical propellants.  

Paul Sullivan

Paul Sullivan is the Managing Director of DH Industries Limited – a part of the Pamasol organisation that specialises in turnkey equipment solutions for aerosol and spray product manufacturing. With over 35 years at DH industries, Paul has extensive experience – from R&D installations to full scale production lines – and leads the company in technical and business development capacities. Paul is an active member of BAMA and frequently speaks at industry events.

Why this roundtable?

This exclusive roundtable offers practical insight into the current challenges faced by the industry experts already pioneering the green transition. Featuring thought leaders from Bespak, DH Industries and Orbia, the panel uniquely focuses on hidden challenges and retrospective learning to better support the industry in its adoption of next-generation propellants.

In a concise 30-minute discussion the panel share their essential learnings on:

  • The current industry landscape and factors driving the transition forward

  • Blind spots to watch out for when planning for the transition

  • Considerations for in-house investment and outsourcing

  • Navigating complex and changing regulatory environments

  • Scaling small-batch testing to commercial production with next-generation propellants

  • Tackling the updated safety and handling requirements

  • Ensuring continuous supply of vital medicines for patients during the transition

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